Experiencia en trasplante pulmonar pediátrico en Chile

Abstract

Lung transplantation (TP) is a treatment option in children with terminal lung diseases. Objective: To evaluate the results and survival of pediatrics lung transplant patients. Methods: Retrospective analysis of clinical records of lung transplantation of patients < 15 years from Clínica Las Condes, Santiago, Chile. Demographic data, type of transplant, baseline and post transplant lung function, early and late complications and survival rate were analyzed. Results: Nine patients < 15 years-old were transplanted. The average age at transplant was 12.7 years. The main indication was cystic fibrosis (7 patients). The average BMI was 17.6 and all the patients were with home oxygen therapy. 77% used extracorporeal intraoperative support. Average baseline FEV₁ was 25.2% with progressive improvement in FEV₁ of 77% in the first year. The main early complications were hemorrhage and primary graft dysfunction, while late complications were infections and chronic graft dysfunction. Four patients have died and the estimated 2 years survival was 85%. They achieved school reinsertion and three managed to complete university studies. Conclusion: Lung transplantation is an alternative for children with advanced lung diseases improving their survival and quality of life.