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MONICA GUTIÉRREZ N NICOLÁS SÁNCHEZ D MARÍA CAROLINA CUELLAR G MARÍA ANGÉLICA RODRÍGUEZ S ALVARO UNDURRAGA P

Abstract

Idiopathic pulmonary fíbrosis (LPF) is the most frecuent of idiopathic interstitial pneumonías. The most sensltlve lung function testfor its diagnosis is a low DLCO register. Objective: To analyze LPF's cllnlcal features and to establish its functional disability by DLCO at the time of diagnosis and also to correlate DLCO with 6-minute walked distance test (DR6), saturation pre andpost DR6 and forcea vital capacity (FVC). Methods: We studied retrospective data from 31 patients with LPF, analyzing personal and family history. We also determined pulmonary function parameters: DLCO (stratified in 4 groups: normal, mild, modérate and severe impairment), FVC, DR6 with pre andpost oxygen saturation. Functional impairment according to DLCO was severe in 7patients and modérate in 19 out ofthe 31 patients. Results: An inverse association was observed between DLCO impairment and oxygen saturation levéis in rest, exercise and the difference between them (p < 0.001). Conclusión: Oxygen saturation level in exercise and rest, as well as the difference between them, have a good correlation with DLCO for LPF diagnosis.

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Keywords.

Idiophatic pulmonary fíbrosis, diagnosis, DLCO

Section
ORIGINAL ARTICLE

How to Cite

GUTIÉRREZ N, M., SÁNCHEZ D, N., CUELLAR G, M. C., RODRÍGUEZ S, M. A., & UNDURRAGA P, A. (2008). Pulmonary function impairment in patients with idiopathic pulmonary fibrosis. Revista Chilena De Enfermedades Respiratorias, 24(4), 279–285. Retrieved from https://revchilenfermrespir.cl/index.php/RChER/article/view/514

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