Role of bacterial lysates in asthma, evidence and projection with special reference to OM-85

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Published Oct 24, 2019

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Daniel Zenteno A.
Pediatra Broncopulmonar, Servicio de Pediatría, Hospital Guillermo Grant Benavente, Concepción. Profesor Asistente, Departamento de Pediatría, Universidad de Concepción. Concepción
Javiera Díaz S.
Interna medicina, Universidad de Concepción. Concepción
Arnoldo Quezada L.
Pediatra Broncopulmonar, Profesor Titular, Departamento de Pediatría y Cirugía Infantil, Campus Sur, Facultad de Medicina, Universidad de Chile. Santiago

Abstract

There are several bacterial lysates, being OM-85 (Broncho-Vaxom®) the one with the greatest evidence regarding its immunoprotective role on respiratory infections in the pediatric population. Its mechanisms of action produce immunomodulatory effects that could potentially prevent asthma in early stages of life, act on the reduction of crisis and be a contribution to conventional asthma therapy. This article shows the main evidences in relation to these compounds, the current focus and future development, especially on OM-85.

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Keywords.

Bacterial lysate, asthma, OM-85, child

Issue
Vol. 35 No. 3 (2019): Revista Chilena de Enfermedades Respiratorias
Section
REVIEWS
Copyright.
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

Zenteno A., D. ., Díaz S., J., & Quezada L., A. (2019). Role of bacterial lysates in asthma, evidence and projection with special reference to OM-85. Revista Chilena De Enfermedades Respiratorias, 35(3), 219–224. Retrieved from https://revchilenfermrespir.cl/index.php/RChER/article/view/842